Tensions grow in Mutant Town as old friends and enemies return, and new friends return older! Karai searches for two new powerful mutants who could tip the balance of power in New York City, and a familiar character from the future arrives with a most unusual quest. Plus, the return of Casey Jones, and Bebop and Rocksteady! Then, when Jennika comes face to face with the person who almost killed her, will the other Turtles be able to stop her from exacting revenge?

Plus, the Shredder returns! Oroku Saki has been to hell and back, but will he now come to the Turtles as friend or foe? Meanwhile, April makes a stand against Baxter Stockman—with dangerous consequences—and the Mutanimals take drastic steps that will put them on a collision course with the TMNT! And Jennika is back for another solo adventure descending into the depths of Mutant Town to unravel a terrible mystery affecting its citizens!

Collects Teenage Mutant Ninja Turtles issues #113–124 and the Jennika II miniseries.